Lectin Magnetic Bead Array for Biomarker Discovery
نویسندگان
چکیده
منابع مشابه
Magnetic track array for efficient bead capture in microchannels.
Magnetism-based microsystems, as those dedicated to immunoaffinity separations or (bio)chemical reactions, take benefit of the large surface area-to-volume ratio provided by the immobilized magnetic beads, thus increasing the sensitivity of the analysis. As the sensitivity is directly linked to the efficiency of the magnetic bead capture, this paper presents a simple method to enhance the captu...
متن کاملProtein Array-based Approaches for Biomarker Discovery in Cancer
Biomarkers are deemed to be potential tools in early diagnosis, therapeutic monitoring, and prognosis evaluation for cancer, with simplicity as well as economic advantages compared with computed tomography and biopsy. However, most of the current cancer biomarkers present insufficient sensitivity as well as specificity. Therefore, there is urgent requirement for the discovery of biomarkers for ...
متن کاملCancer Biomarker Discovery: Lectin-Based Strategies Targeting Glycoproteins
Biomarker discovery can identify molecular markers in various cancers that can be used for detection, screening, diagnosis, and monitoring of disease progression. Lectin-affinity is a technique that can be used for the enrichment of glycoproteins from a complex sample, facilitating the discovery of novel cancer biomarkers associated with a disease state.
متن کاملBead-based multianalyte flow immunoassays: the cytometric bead array system.
Analytical cytometry has significant potential beyond cellular analysis. The inherent capability of flow cytometers to efficiently discriminate between uniformly sized particles based on their intrinsic properties provides the foundation for multiplex bead assays. The technology can be exploited in designing immunoassays, Western blot-like antibody assays, and nucleic acid hybridization assays....
متن کاملMetabolomics for Biomarker Discovery
Metabolomics is the study of the small molecule biochemistry of an organism. The goal is to understand the metabolic state of a subject by extracting, identifying and quantifying all of the small molecule compounds (for example, metabolites) in a biological sample. Since it is based upon biochemistry and provides a measurement of the biological status of an organism, metabolomics provides a pow...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2010
ISSN: 1535-3893,1535-3907
DOI: 10.1021/pr100472z